This visualization adapted from the University of Massachusetts Medical School shows the process by which a dengue virus releases its genetic contents inside a host cell, allowing viral replication. The key players are proteins found on the viral surface called envelope proteins, which change their structure when the virus is endocytosed, or taken inside the cell. This structural change enables the viral membrane to fuse with the endosomal membrane, and the virus' RNA to enter the cytoplasm of a host cell. There, ribosomes will make viral proteins that will spread to other cells through the replication and secretion of new viral particles.