The story of two Lakota women who work to expose the human cost of uranium mining and its impact on sacred water.  Debra White Plume is a grandmother and tireless leader in the fight to protect her people's water and land from corporate polluters.  Debra is the lead plaintiff in a case challenging uranium mining on Lakota treaty territory.  Elisha Yellow Thunder intimately understands the dangers of contaminated water.  A young mother and a geology student, she unknowingly drank water with high levels of radiation while pregnant with her first daughter, whose severe medical anomalies are life-threatening.

Crying Earth Rise Up documents the growing movement of Native and non-native people of the Great Plains in their battle to stop the expansion of uranium mining.

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